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Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues (World Health Organization Classification of Tumours) by Elaine Sarkin Jaffe

Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues (World Health Organization Classification of Tumours) Elaine Sarkin Jaffe ebook
Format: pdf
ISBN: 9283224116, 9789283224112
Page: 352
Publisher:

Extra-nodal NK/T -cell lymphoma (ENKTL) is a relatively recently characterised clinicopathological entity, being formally incorporated into the WHO classification of haematopoietic and lymphoid tumours in 1999 [86]. Leukemias are classified according to clinical, morphologic, and immunologic phenotypes, caused by specific genetic aberrations in association to distinct prognostic profiles. The recent and ongoing rapid WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. In the late 1970s and early 1980s the term “reticulum cell sarcoma” became a misnomer as researchers demonstrated the origin of the tumor cells to be transformed lymphoid cells (malignant B- and T- lymphocytes), not histiocytes. In 1982 With the advancement of immunology and genetics, the characterization and algorithm of lymphomas have been taken over by the World Health Organization (WHO) Lymphoma Classification. WHO Classification of Tumours of the Digestive System, Fourth Edition. Specimens from all patients with a diagnosis of ophthalmic lymphoma in Denmark during the period 1980 to 2005 were reviewed and reclassified according to the World Health Organization (WHO) classification. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Primary brain tumours in adults. - WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, Fourth Edition. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack and eradicate tumor cells at molecular level and significantly impacted our current therapeutics for hematological malignancies. World Health Organization Classification of Tumours. There followed a series of reports, predominantly from Japan and East Asia, demonstrating the striking pathological feature of EBV-infected T or NK cells in the blood or tissue of affected patients [20-26]. Cases reclassified as EMZL were selected and reviewed with respect to clinical characteristics and ..